Weekly issue 2026-W37 ·
Increased risk of incident and recurrent urinary tract infection in autosomal dominant polycystic kidney disease: a contemporary propensity score-matched cohort study
Plain language
In a large Taiwanese matched study, about 18% of adults with ADPKD got a urinary tract infection over follow-up versus about 16% of similar people without cystic kidney disease — a modest absolute rise, but the risk of first and repeat UTIs was still higher, especially in men and in more advanced CKD. Worth watching symptoms early and talking prevention with your clinicians.
Clinical note
PS-matched cohort NTUH 2006–2021 (1,044 ADPKD vs 4,176 controls; prior UTI excluded; mean follow-up 4.2 y). Incident UTI 17.9% vs 15.6% (aHR 1.20, 95% CI 1.02–1.42); stronger in males (aHR 1.59) and CKD stages 3b–5 (aHR 1.51). Recurrent UTI IRR 1.32 (95% CI 1.15–1.51). Contemporary epidemiology with moderate absolute difference; residual confounding and ICD limits on separating cyst infection remain.
Question for your next visit
Which urinary infection symptoms should I report promptly, and what prevention steps fit my kidney health?