Weekly issue 2026-W33 ·
Prognostic Performance of Ellipsoid Kidney Volume Measurement in a Computed Tomography-Heavy ADPKD Cohort: A Retrospective Observational Cohort Study.
Plain language
Deciding who qualifies for tolvaptan hinges on precise kidney measurements — usually traced by hand on scans. In 151 Canadian patients, a quick ellipsoid formula on mostly CT scans matched hand-tracing well enough to flag high-risk disease. Handy where MRI is scarce.
Clinical note
Retrospective agreement study, Ottawa clinic (107 CT plus 44 MRI). Ellipsoid versus manual height-adjusted TKV for Mayo classification and high-risk (1C–1E) disease. Single center — supports CT-based stratification locally, validate before adopting.
Question for your next visit
How was my kidney size measured, and could uncertainty in that measurement affect discussions about my risk or treatment options?